In-111 labeled WBC

Indications: Inflammatory bowel disease, orthopedic hardware, prior fracture

Contraindications: WBC count less than 5K


Questions asked in Patient History:

1- Any recent surgical procedure
2- Any history of chronic pain
3- Any orthopedic hardware recently inserted
4-Possibility of bring pregant or breastfeeding

Radiopharmaceutical information:
  • Radionuclide: Indium 111
  • Radiopharmaceutical: Oxine WBC
  • Adult dosing: 0.5 uCi
  • Pediatric dosing:
  • Method of administration: Intravenous
  • Method of Localization:
  • Physical Half-life: 67 hours

Patient Preparation:

No patient preperation is needed for this procedure.

Side Effects:

Will the patient feel any different during or after the procedure?

Equipment Used:
Type of Camera or Probe
Collimator used: MEGP

Acquisition Setup:

Photopeak(s): 173 and 247

Window(s): 20%


Dynamic: View(s)
Matrix:
Time/Frame:
Number of Frames:

Statics: View(s)
Matrix:
Total Counts or Duration:

Whole body: View(s)
Matrix: 512x1024
Scan Speed: 6cm/min
Start/stop points: head to toe

SPECT:
180 or 90 degree configuration
Total Rotation: 180
Starting point: 45 degree
Matrix: 128x128x16
Time/Azmuiths
Number of Azmuiths: 64

Processing:


Filter:
Cut-off:
Frequency:


Procedure:
1- No patient preparation needed for this procedure.
2- Blood obtain from patient prior to procedure, blood send to radiopharmacy to be labeled.
3- Administer IV 0.5 mCi of labeled In-111 oxine WBC via a 18 gauge needle.
4- Imaging time begin 4 hour post injection.
5- whole body parameters; views: anterior and posterior; scan speed 6cm/minute, 500K counts of the abdomen.
6- if need be spect study is requested, parameters would include: 180 degree rotation, 40 seconds/frame, 32 frames/projection.

Normal Uptake and common varients:

Normal bio-distribution in specific organs such as liver, bone marrow and spleen are usually visualize in scan.

Abnormal Uptake and causes:

Any other site where the radiopharmaceutical is more intense than the liver and less than the bone marrow would consider very serious.


Artifacts:
Several abormalities may alter true diagnosis if adequate patient is not taken. these artifacts are: feeding tube, colostomy bag, healing fracture and surgical wounds.


References: